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	Provedor de dados Biocell (1) BJMBR (1) BJPS (1) Autor Garcia,L.V. (1) Hong,Samin (1) Je Seong,Gong (1) Kab Kim,Seung (1) Kaya,Kürşat (1) Leite,J.P. (1) Lima,J.E. (1) Takayanagui,O.M. (1) Taşlıdere,Elif (1) Türkmen,Neşe Başak (1) Yoko,Iizuka (1) Yun Kim,Chan (1) Çiftçi,Osman (1) Öztanır,Mustafa Namık (1) Mais... Palavra-chave Neuronal damage (3) Albumin quotient (1) Apoptosis (1) Beta-glucan (1) C57BL/J6 mice (1) Cerebrospinal fluid (1) Global cerebral I/R (1) Neuron-specific enolase (1) Neuroprotection (1) Oxidative stress (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2019 (1) 2008 (1) 2004 (1) País Brazil (2) Argentina (1) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Agmatine pretreatment protects retinal ganglion cells (RGC-5 cell line) from oxidative stress in vitro Biocell Yoko,Iizuka; Hong,Samin; Yun Kim,Chan; Kab Kim,Seung; Je Seong,Gong. Agmatine, 2-(4-aminobutyl)guanidine, has been reported to have neuroprotective effects against various neuronal damages. In this study it was investigated whether agmatine pretreatment rescues the retinal ganglion cells from oxidative injury in vitro. After differentiation of transformed rat retinal ganglion cells (RGC-5 cell line) with staurosporine, agmatine (0.0 to 100.0 μM) pretreatment was performed for 2 hours. Subsequently, they were exposed to hydrogen peroxide (0.0 to 2.5 mM) as an oxidative stress. Cell viability was monitored for up to 48 hours with the lactate dehydrogenase (LDH) assay and apoptosis was examined by the terminal deoxynucleotide transferase-mediated terminal uridine deoxynucleotidyl transferase nick end-labeling (TUNEL)... Tipo: Info:eu-repo/semantics/article Palavras-chave: Neuronal damage; Apoptosis; Neuroprotection. Ano: 2008 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452008000300005 Beta-glucan attenuates cerebral ischemia/reperfusion-induced neuronal injury in a C57BL/J6 mouse model BJPS Kaya,Kürşat; Çiftçi,Osman; Öztanır,Mustafa Namık; Taşlıdere,Elif; Türkmen,Neşe Başak. Beta-glucans (βg), that have many useful effects on human health, are natural polysaccharides. Our aim in this study was to determine useful effect of βg against oxidative and neuronal damage caused by global cerebral ischemia/reperfusion (IR) in stroke imitated mice via surgical operation. A total of 40 mice divided into four equal groups randomly. The group 1 (sham operated) was kept as control. Bilateral carotid arteries of subjects in group 2 (I/R) and group 4 (I/ R + βg) were clipped for 15 min, and the mice in group 4 (I/R + βg) were treated with βg (50 mg/kg/day), while the mice in group 2 (I/R) were treated with only vehicle for 10 days. The mice of group 3 (βg) were treated with βg for 10 days without carotid occlusion. Global cerebral I/R... Tipo: Info:eu-repo/semantics/article Palavras-chave: Global cerebral I/R; Oxidative stress; Neuronal damage; Beta-glucan; C57BL/J6 mice. Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100570 Use of neuron-specific enolase for assessing the severity and outcome of neurological disorders in patients BJMBR Lima,J.E.; Takayanagui,O.M.; Garcia,L.V.; Leite,J.P.. Neuron-specific enolase (NSE) is a glycolytic enzyme present almost exclusively in neurons and neuroendocrine cells. NSE levels in cerebrospinal fluid (CSF) are assumed to be useful to estimate neuronal injury and clinical outcome of patients with serious clinical manifestations such as those observed in stroke, head injury, anoxic encephalopathy, encephalitis, brain metastasis, and status epilepticus. We compared levels of NSE in serum (sNSE) and in CSF (cNSE) among four groups: patients with meningitis (N = 11), patients with encephalic injuries associated with impairment of consciousness (ENC, N = 7), patients with neurocysticercosis (N = 25), and normal subjects (N = 8). Albumin was determined in serum and CSF samples, and the albumin quotient was used... Tipo: Info:eu-repo/semantics/article Palavras-chave: Neuronal damage; Neuron-specific enolase; Cerebrospinal fluid; Albumin quotient. Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000100003 Registros recuperados: 3 Primeira ... 1 ... Última

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